My guest is Eddie Chang, MD, a neurosurgeon and professor of neurological surgery at the University of California, San Francisco (UCSF) and the co-director of the Center for Neural Engineering & Prostheses. We discuss the brain mechanisms underlying speech, language learning and comprehension, communicating human emotion with words and hand gestures, bilingualism and language disorders, such as stuttering. Dr. Chang also explains his work developing and applying state-of-the-art technology to decode speech and using that information and artificial intelligence (AI) to successfully restore communication to patients who have suffered paralyzing injuries or “locked in syndrome.” We also discuss his work treating patients with epilepsy. Finally, we consider the future: how modern neuroscience is overturning textbook medical books, the impact of digital technology such as smartphones on language and the future of natural and computer-assisted human communication.

#HubermanLab #Science #Neuroscience

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Dr. Eddie Chang
Support research in the Chang Laboratory: https://changlab.ucsf.edu/support-our-work
Dr. Chang’s lab: https://changlab.ucsf.edu
Academic profile & publications: https://profiles.ucsf.edu/edward.chang
UCSF clinical profile: https://www.ucsfhealth.org/providers/dr-edward-chang

Articles
Neuroprosthesis for Decoding Speech in a Paralyzed Person with Anarthria: https://bit.ly/3sjv5Cx

Articles in the News
Tapping Into the Brain to Help a Paralyzed Man Speak: https://nyti.ms/3f0AM5c
How Brain-Computer Interfaces Could Restore Speech and Help Fight Depression: https://on.wsj.com/3f1iBMH
Decoded Brain Signals Could Give Voiceless People A Way To Talk: https://n.pr/3gujhdP

Timestamps
00:00:00 Dr. Eddie Chang, Speech & Language
00:03:00 Levels, Eight Sleep, InsideTracker, Momentous Supplements
00:07:19 Neuroplasticity, Learning of Speech & Environmental Sounds
00:13:10 White Noise Machines, Infant Sleep & Sensitization
00:17:26 Mapping Speech & Language in the Brain
00:24:26 Emotion; Anxiety & Epilepsy
00:30:19 Epilepsy, Medications & Neurosurgery
00:33:01 Ketogenic Diet & Epilepsy
00:34:56 AG1 (Athletic Greens)
00:36:10 Absence Seizures, Nocturnal Seizures & Other Seizure Types
00:41:08 Brain Areas for Speech & Language, Broca’s & Wernicke’s Areas, New Findings
00:53:23 Lateralization of Speech/Language & Handedness, Strokes
00:59:05 Bilingualism, Shared Language Circuits
01:01:18 Speech vs. Language, Signal Transduction from Ear to Brain
01:12:38 Shaping Breath: Larynx, Vocal Folds & Pharynx; Vocalizations
01:17:37 Mapping Language in the Brain
01:20:26 Plosives & Consonant Clusters; Learning Multiple Languages
01:25:07 Motor Patterns of Speech & Language
01:28:33 Reading & Writing; Dyslexia & Treatments
01:34:47 Evolution of Language
01:37:54 Stroke & Foreign Accent Syndrome
01:40:31 Auditory Memory, Long-Term Motor Memory
01:45:26 Paralysis, ALS, “Locked-In Syndrome” & Brain Computer Interface (BCI)
02:02:14 Neuralink, BCI, Superhuman Skills & Augmentation
02:10:21 Non-Verbal Communication, Facial Expressions, BCI & Avatars
02:17:35 Stutter, Anxiety & Treatment
02:22:55 Tools: Practices for Maintaining Calm Under Extreme Demands
02:31:10 Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Huberman Lab Premium, Neural Network Newsletter, Social Media

Huberman Lab is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.

Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com